Mesotherapy is a mildly invasive procedure able to improve the skin’s hydration and its mechanical properties and to resolve the unsightly appearance of cellulite. It is carried out by practicing several subcutaneous injections of low quantities of active substances (hyaluronic acid, vitamins, antioxidants, enzymes, humectants) with the aim of stimulating the biosynthetic capacity of fibroblasts, increasing the production of collagen and elastin and providing molecules essential for fibroblasts .

In a study published in the Journal of Cosmetic and Laser Therapy 2017, 21 women with cellulitis were subjected to a series of procedures of intradermal mesotherapy, evaluating the following parameters: thickness of the epidermis, dermis and hypodermis, echogenicity of the dermis and surface area of ​​the serrated hypodermis-dermis junction. Furthermore, the circumference of the thigh, the body mass index was measured, while the severity of cellulite was assessed on a photographic basis using the Nürnberger-Müller scale. Intradermal mesotherapy descreased the severity of cellulite: the thickness of the hypodermis reduced significantly. Cellulite reduction was also evident by palpation, reduced thigh circumference, and Nürnberger-Müller degree. Intradermal mesotherapy is confirmed to be effective in reducing cellulite.

Sylwia, Malinowska, and Mlosek Robert Krzysztof. “Efficacy of intradermal mesotherapy in cellulite reduction-conventional and high frequency ultrasound monitoring results.” Journal of Cosmetic and Laser Therapy just-accepted (2017).